Short, peer-reviewed articles on compounds, food matrices, biomolecular pathways, and dietary patterns. Every claim cites primary literature.
Curcumin is poorly absorbed alone. Piperine from black pepper shifts serum concentrations from undetectable to measurable. Here is what the primary evidence actually shows.
Dietary PatternsThe PREDIMED trial is the most rigorous dietary intervention ever run. What it found, what was corrected, and why the effect held after reanalysis.
BioactivesDecaffeinated coffee reduces type 2 diabetes risk just as well as caffeinated coffee. The evidence that polyphenols — not caffeine — are responsible.
EpidemiologyA 4× difference in Alzheimer's prevalence between rural India and Pennsylvania, measured with identical methods. What the data shows and what it cannot prove.
Eating PatternsAutophagy won the 2016 Nobel Prize. How fasting activates it via mTOR suppression, and what human trials actually show about eating windows.
These open preprints support the coffee and bioactive analysis referenced across our nutrition articles. Articles stay in Insights; source papers live as downloadable PDFs.
Computational docking study for coffee diterpenes and cholesterol metabolism targets. Download PDF →
Network pharmacology map for six major coffee bioactives across cardiometabolic pathways. Download PDF →
Quantum chemistry and multi-scale model of coffee roasting chemistry and melanoidin formation. Download PDF →
Absorption, distribution, metabolism, excretion, toxicity, and brewing-method bioavailability analysis. Download PDF →
Each article in this section is written to the same evidence standard we apply to client research reports. Every specific number, effect size, or molecular claim cites the original peer-reviewed paper with PMID or DOI. Associations are distinguished from causation. Limitations are stated within each piece.